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Updated: Jul 19, 2026

Creation of a Rodent Model of Abdominal Aortic Aneurysm by Blocking Adventitial Vasa Vasorum Perfusion
Published on: November 8, 2017
Abdominal aortic aneurysm associated with abdominal visceral diseases
L Leone1, C Germiglio, R Monteforte
1Unit of Vascular Surgery, Umberto I Hospital, Siracusa, Italy. leonesr@tin.it
Abstract:
Abdominal aortic aneurysm (AAA) occurs in advanced age. As such, its frequency has increased with the general ageing of the population as has the possibility of finding AAA associated with abdominal visceral disease, especially neoplasms. A malignant mass is present in 4% of patients who undergo aortic reconstruction for AAA. Since surgical treatment for both is often potentially life-threatening, the surgeon is faced with a series of treatment decisions concerning foremost timing of the operation. The main worry is that simultaneous treatment carries a potential risk of infection of the vascular graft. On the other hand, a 2-phase procedure is also burdened by risks linked to a second anaesthesia and a second surgical operation carried out on scar or contaminated tissue and the worsening of one of the 2 potentially life-threatening illnesses. In this situation endovascular treatment of an AAA may represent an advantageous alternative therapeutic strategy.
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