Related Experiment Video
Updated: Jul 19, 2026

11:20
Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021
Branch retinal vein occlusion associated with vitreoretinal traction
T Mark Johnson1, Christopher W Vaughn, Bert M Glaser
1The National Retina Institute, Chevy Chase, MD 20815, USA. mjohnson@bmgnri.com
Summary
Vitreoretinal traction may contribute to branch retinal vein occlusion (BRVO) development. This case series suggests that traction, not just arteriovenous crossing, plays a role in BRVO pathogenesis.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Vascular Disorders
Background:
- Branch retinal vein occlusion (BRVO) is commonly associated with arteriovenous crossing sites.
- The role of vitreoretinal traction in BRVO pathogenesis is not fully understood.
- Surgical interventions for BRVO exist, but successful outcomes may depend on vitreous detachment.
Observation:
- A retrospective review of three patients with BRVO and evidence of vitreoretinal traction was conducted.
- Patients presented with mild vitreous hemorrhage and linear intraretinal hemorrhages.
- Diagnostic imaging revealed partial avulsion of the affected venous segment.
Findings:
- Vitreoretinal traction was observed at the site of venous occlusion in all patients.
- Fluorescein angiography showed delayed venous flow and blocked fluorescence due to hemorrhage.
- Clinical examination, B-scan ultrasound, and OCT confirmed partial venous avulsion.
Implications:
- Vitreoretinal traction may be a significant contributing factor in the development of BRVO in select cases.
- Understanding the role of vitreoretinal traction could refine treatment strategies for BRVO.
- Further research is warranted to elucidate the precise mechanisms linking vitreoretinal traction and BRVO.
Related Concept Videos
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Diabetic Retinopathy
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
