Related Experiment Video
Updated: Jul 19, 2026

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
Published on: May 15, 2020
The development of clinical prediction guides requires reproducible decision-making outputs: a field study
1School of Medicine and Postgraduate School of Occupational Medicine, Occupational Health Unit, Teaching hospital, University of Modena and Reggio Emilia, Modena, Italy. franco@unimo.it
Background:
The decisions taken by occupational physicians (OPs) generally show low reproducibility and reflect some uncertainties linked to the decision making process.
Aim:
The aim of the study was to evaluate the variability of different OP decisions in order to assess their reproducibility, which is regarded as a quality factor of the professional practice.
Methods:
4 OPs examined the records of 100 selected hospital workers with impaired health conditions in order to take decisions about job fitness, advice to workers, referral to clinical physician, need for further investigations, report of occupational disease and recommendation for the general practitioner. The variability of inter-individual decision was measured by percent agreement and Cohen's kappa test.
Results:
After accounting for variability expected by chance, the agreement among decisions on job fitness ranged from fair to substantial, but high variability was observed for most other assessments.
Conclusion:
The observed inter-individual variability for some decisions taken by different OPs represents a crucial aspect to be dealt with, as the reproducibility of medical decisions is indispensable for the clinical prediction guides to be built and adopted for improving the practice.
Related Concept Videos
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Clinical Trials
There are four phases in a clinical trial. A phase one...
Statistical Software for Data Analysis and Clinical Trials
Preclinical Development: Overview
Sensitivity, Specificity, and Predicted Value
Sensitivity is the...
Decision Making: P-value Method
First, a specific claim about the population parameter is proposed. The claim is based on the research question and is stated in a simple form. Further, an opposing statement to the claim is also stated. These statements can act as null and alternative hypotheses: a null hypothesis would be a neutral statement while the alternative hypothesis can have a...