Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Complex regional pain syndrome.

N Bogduk1

  • 1Newcastle Bone and Joint Institute, University of Newcastle, Royal Newcastle Hospital, Newcastle, New South Wales, Australia. mgillam@mail.newcastle.edu.au

Current Opinion in Anaesthesiology
|October 5, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A retrospective analysis of chronic subdural haematoma recurrence rates following burr hole trephination versus minicraniotomy.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2018
Same author

Evidence of effectiveness of a fracture liaison service to reduce the re-fracture rate.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2015
Same author

The innervation of the vertebral column.

The Australian journal of physiotherapy·2014
Same author

Instantaneous axes of rotation of the typical cervical motion segments: a study in normal volunteers.

Clinical biomechanics (Bristol, Avon)·2013
Same author

The morphology of the human lumbar multifidus.

Clinical biomechanics (Bristol, Avon)·2013
Same author

The biomechanics of the lumbar multifidus.

Clinical biomechanics (Bristol, Avon)·2013
Same journal

The evolution of nonoperating room anesthesia: navigating a new frontier.

Current opinion in anaesthesiology·2026
Same journal

Enhanced recovery pathways for patients with chronic pain: beyond standard protocols - a narrative review.

Current opinion in anaesthesiology·2026
Same journal

Novel technologies and innovations in postoperative follow-up after regional anesthesia.

Current opinion in anaesthesiology·2026
Same journal

Regional anaesthesia and analgesia in surgical patients with chronic preoperative pain: mechanisms, evidence, and clinical implications.

Current opinion in anaesthesiology·2026
Same journal

Retention in pain care and research: a narrative review focused on implanted medical devices.

Current opinion in anaesthesiology·2026
Same journal

Airway ultrasound in patients undergoing head and neck surgery.

Current opinion in anaesthesiology·2026
See all related articles

Complex regional pain syndrome (CRPS) diagnosis and treatment remain challenging, with debate over terminology and underlying mechanisms. Emerging evidence suggests central nervous system involvement and potential benefits from bisphosphonates and spinal cord stimulation.

Area of Science:

  • Pain Medicine
  • Neurology
  • Rehabilitation Medicine

Background:

  • The term 'complex regional pain syndrome' (CRPS) is recommended but not widely adopted, with 'reflex sympathetic dystrophy' still preferred.
  • Diagnostic criteria for CRPS lack specificity, prompting proposals for refined criteria.
  • The pathophysiology of CRPS is not fully understood, with ongoing debate between central and peripheral mechanisms.

Purpose of the Study:

  • To review the current understanding of complex regional pain syndrome (CRPS).
  • To discuss diagnostic challenges and proposed criteria.
  • To explore current and emerging treatment options for CRPS.

Main Methods:

  • Literature review of studies on CRPS terminology, diagnosis, pathophysiology, and treatment.

Related Experiment Videos

  • Analysis of proposed diagnostic criteria and their limitations.
  • Evaluation of evidence for various therapeutic interventions.

    • Main Results:

    • CRPS terminology remains inconsistent, hindering widespread adoption of the recommended term.
    • Central mechanisms are favored for sensory and autonomic features, though peripheral factors like tissue acidosis are considered.
    • Controlled studies suggest potential efficacy of bisphosphonates and spinal cord stimulation for CRPS treatment.

    Conclusions:

    • Standardized terminology and refined diagnostic criteria are needed for CRPS.
    • Further research into CRPS pathophysiology is crucial.
    • Evidence supports exploring bisphosphonates and spinal cord stimulation as treatment options for CRPS.