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Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting
Published on: June 21, 2024
How can we best prevent or treat postoperative nausea and vomiting?
1Department of Anesthesiology, Mayo Clinic Scottsdale, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA. leslie.john@mayo.edu
New studies offer improved tools for predicting and preventing postoperative nausea and vomiting (PONV). A multimodal approach combining anti-emetics, steroids like dexamethasone, and avoiding opioids is most effective for PONV prevention.
Area of Science:
- Anesthesiology
- Clinical Pharmacology
Background:
- Postoperative nausea and vomiting (PONV) remains a significant concern for patient recovery.
- Effective prevention and management strategies are crucial for improving surgical outcomes.
Purpose of the Study:
- To review current clinical studies on preventing and managing postoperative nausea and vomiting.
- To identify updated risk prediction tools, cost-effective anti-emetics, and optimal prophylactic strategies.
Main Methods:
- Analysis of recent clinical studies and trials.
- Evaluation of risk factors and comparative effectiveness of anti-emetic interventions.
- Assessment of multimodal prophylactic approaches.
Main Results:
- Revised risk prediction tools and stratification formulae for identifying high-risk patients.
- Comparative trials suggest specific anti-emetics and the addition of steroids (dexamethasone) are beneficial.
- Key risk factors for PONV include female sex, history of PONV/motion sickness, young age, volatile anesthetics, nitrous oxide, and opioid administration.
Conclusions:
- Multimodal prophylaxis is the most successful approach to preventing postoperative nausea and vomiting.
- This includes combination anti-emetics, dexamethasone, adequate hydration, opioid avoidance, and robust pain management.
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