Related Experiment Video
Updated: Jul 19, 2026

Laminectomy and Spinal Cord Window Implantation in the Mouse
Published on: October 23, 2019
Multiple sclerosis and anesthetic implications
Ihab R Dorotta1, Armin Schubert
1Department of General Anesthesiology, Cleveland Clinic Foundation, Cleveland, Ohio, USA. Dorotti@ccf.org
Purpose Of Review:
Multiple sclerosis remains prevalent among young women in the United States of America. It is a disease of the central nervous system that possesses many anesthetic implications. Anesthesia providers need to understand this disorder and its multiple anesthetic ramifications.
Recent Findings:
Recent work has provided more insight into the etiology of multiple sclerosis, its pathogenesis, diagnosis and natural history. A number of new medications have also been added to the therapeutic armamentarium. Optimal anesthetic care entails a thorough preoperative evaluation, medication history and neurologic examination, intraoperative awareness of conditions that may precipitate attacks and lead to potentially life-threatening complications, as well as postoperative attention to respiratory and other risks. Recommendations for management are based on information from small retrospective studies and anecdotal reports.
Summary:
In summary, our aim is to provide an updated view of multiple sclerosis from the perspective of perioperative care, emphasizing interactions between the disease, surgery and anesthesia.
Related Concept Videos
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Local Anesthetics: Adverse Effects
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Local Anesthetics: Clinical Application as Spinal Anesthesia
Skeletal Muscle Relaxants: Therapeutic Uses
Parenteral Anesthetics: Overview
Inhalational Anesthetics: Overview
