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Updated: Jul 19, 2026

Characterizing Electron Transport through Living Biofilms
Published on: June 1, 2018
On the electron transfer mechanism between cytochrome C and metal electrodes. Evidence for dynamic control at short
Hongjun Yue1, D Khoshtariya, D H Waldeck
1Chemistry Department, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.
Abstract:
Cytochrome c was coordinatively bound to self-assembled monolayers of pyridine-terminated alkanethiols on Au and Ag electrodes. The mechanism of heterogeneous electron transfer of the immobilized protein was investigated by cyclic voltammetry and time-resolved surface-enhanced resonance Raman spectroelectrochemistry. The temperature, distance, and overpotential dependencies of the electron transfer rates indicate a change of mechanism from a tunneling controlled reaction at long distances (thicker films) to a solvent/protein friction controlled reaction at smaller distances (thinner films).
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