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Updated: Jul 19, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
10:28

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function

Published on: March 15, 2022

[Descriptive study of vascular complications secondary to antithrombotic agents and percutaneous cardiovascular

Ana Rosa Alconero Camarero1, María Casáus Pérez, Luz Elena Mirones Valdeolivas

  • 1Escuela Universitaria de Enfermería Casa de Salud Valdecilla, Universidad de Cantabria, Santander, España. alconear@unican.es

Enfermeria Intensiva
|October 6, 2006
PubMed

Insights

Vascular complications like hematomas and femoral bleeding occur in 39% of patients receiving antithrombotic drugs and percutaneous transluminal coronary angioplasty (PTCA). Arterial sheath duration is a key factor contributing to these bleeding events.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Interventional Cardiology

Background:

  • Antithrombotic drugs significantly reduce morbidity and mortality in acute coronary syndrome patients undergoing percutaneous transluminal coronary angioplasty (PTCA).
  • However, these vital medications increase the risk of bleeding complications following interventional procedures.

Purpose of the Study:

  • To determine the incidence of vascular complications in patients treated with antithrombotic drugs and percutaneous cardiovascular interventions.
  • To identify variables associated with the occurrence of these vascular complications.

Main Methods:

  • A retrospective descriptive study analyzed clinical histories of 153 patients.
  • Patients underwent primary angioplasty or rescue treatment between October 2001 and October 2002.
  • Data included patient demographics, diagnoses (75% acute myocardial infarction), procedure types (71% primary angioplasty), antithrombotic drug use, compression methods, and arterial sheath duration.

Main Results:

  • Vascular complications occurred in 39% of patients.
  • Hematomas were the most frequent complication (28%), followed by femoral bleeding.
  • Increased arterial sheath duration was identified as a significant contributing factor to vascular complications.

Conclusions:

  • Combining antithrombotic drugs with PTCA leads to vascular complications in approximately one-third of patients.
  • Hematomas and femoral bleeding are the predominant complications.
  • Arterial sheath management, specifically its duration, is crucial for minimizing vascular complication risk.

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