Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 19, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
08:05

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane

Published on: December 9, 2022

Prospective randomized study evaluating an absorbable cyanoacrylate for use in vascular reconstructions.

Alan B Lumsden1, Eugene R Heyman,

  • 1Division of Vascular Surgery, Baylor College of Medicine, Houston, TX 77030, USA. alumsden@bcm.tmc.edu

Journal of Vascular Surgery
|October 6, 2006
PubMed
Summary

Cyanoacrylate surgical sealant significantly reduces bleeding time and achieves faster hemostasis in vascular surgery. This effective and safe sealant improves outcomes for patients undergoing arterial vascular anastomoses.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction to: 2025 ACC/AHA/ASE/ASNC/SCCT/SCMR Advanced Training Statement on Advanced Cardiovascular Imaging: A Report of the ACC Competency Management Committee.

Circulation. Cardiovascular imaging·2026
Same author

Cerebral Microembolization Generated by Percutaneously Implanted Microaxial Left Ventricular Assist Device.

Journal of cardiothoracic and vascular anesthesia·2026
Same author

Feasibility of optical coherence tomography for localizing and quantifying paclitaxel deposition after drug-coated balloon angioplasty.

International journal of cardiology·2026
Same author

Retrograde type A aortic dissection following endovascular arch repair: what do clinicians need to be aware of?

Expert review of cardiovascular therapy·2026
Same author

Reply.

Journal of vascular surgery·2026
Same author

Endovascular aortic retrieval of migrated iliac stent.

Journal of vascular surgery cases and innovative techniques·2026

Area of Science:

  • Vascular Surgery
  • Biomaterials
  • Surgical Hemostasis

Background:

  • Anastomotic bleeding is a significant complication in vascular surgery.
  • There is a need for effective and safe vascular sealants.
  • Cyanoacrylate surgical sealant was evaluated for hemostasis in expanded polytetrafluoroethylene (ePTFE) vascular anastomoses.

Purpose of the Study:

  • To evaluate the safety and efficacy of cyanoacrylate surgical sealant.
  • To assess its performance in achieving hemostasis in arterial vascular anastomoses.
  • To compare cyanoacrylate sealant with oxidized cellulose in femoral bypass and arteriovenous (AV) shunt procedures.

Main Methods:

  • A multicenter, randomized, controlled, open-label study involving 151 patients.
  • Patients received either cyanoacrylate surgical sealant or oxidized cellulose (control).

More Related Videos

A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing
20:33

A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing

Published on: July 4, 2019

Related Experiment Videos

Last Updated: Jul 19, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
08:05

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane

Published on: December 9, 2022

A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing
20:33

A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing

Published on: July 4, 2019

  • Primary endpoint: time from clamp release to hemostasis; secondary endpoints: hemostasis at specific time points, need for adjunctive measures, and adverse events.

    • Main Results:

    • Mean hemostasis time was significantly shorter with cyanoacrylate sealant (119.3 seconds) compared to control (403.8 seconds) (P < .001).
    • Immediate hemostasis was achieved in 54.5% of patients with cyanoacrylate sealant versus 10% with control.
    • Fewer patients required additional hemostatic measures with cyanoacrylate sealant, with similar adverse event rates.

    Conclusions:

    • Cyanoacrylate surgical sealant is effective in reducing hemostasis time and achieving immediate hemostasis.
    • The sealant is safe for internal use in vascular surgery.
    • It offers an easy-to-use solution with good safety and efficacy for decreasing anastomotic bleeding.