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Updated: Jun 25, 2026

Biochemical Titration of Glycogen In vitro
Published on: November 25, 2013
[Factors participating in the variability of glycosylated hemoglobin levels]
Rosa María Hermosillo-Bañuelos1, Fernando Rivas, Bertha Ibarraa
1División de Genètica, Centro de Investigación Biomèdica de Occidente, Instituto Mexicano del Seguro Social.
Abstract:
Glycated hemoglobin values are a good indicator of metabolic control of the diabetic patients; however the levels can be influenced by analytic, clinic and biological variability. In the first, it is important to know that the variation coefficient between-laboratory should be < 3-4%; the second, depends on the metabolic control of the patients, while the third is determined by internal and external factors. Family studies had shown that genetic factors are involved in the biological variability of glycated hemoglobin. In order to have a correct interpretation of the glycated hemoglobin levels, it is important to know the causes of variability.
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