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A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
Rupture of a nonaneurysmal aorta secondary to Staphylococcus aortitis
Christopher T Stephens1, Lori L Pounds, Lois A Killewich
1Department of Anesthesiology, Department of Surgery, University of Texas Medical Branch, Galveston, TX 77555-0735, USA.
Abstract:
Infectious aortitis has become increasingly uncommon and, when diagnosed, typically occurs in an immunocompromised elderly male with a history of Staphylococcus or Salmonella infection and underlying atheromatous cardiovascular disease. The authors report a case of a 74-year-old man with aortitis complicated by rupture secondary to Staphylococcus aureus infection. The patient presented with worsening abdominal pain and fever after being discharged from the emergency room 2 weeks before with back pain and leukocytosis diagnosed as urinary tract infection and bronchitis. Computed tomography (CT) imaging of the retroperitoneum on the first visit appeared normal. Repeat CT scan on the subsequent visit revealed a contained rupture of a nonaneurysmal aorta at the level of the diaphragm. The patient was taken to the operating room emergently for repair. An infected periaortic hematoma and a 1 cm perforation in the posterior aorta were found. The aorta was excised and the area debrided. Revascularization was performed using a 22 mm extruded polytetrafluoroethylene (ePTFE) interposition graft placed in situ. This case demonstrates that a high index of suspicion is required in diagnosing infectious aortitis and that the diagnosis may be delayed in many cases. Additionally, it may not be uncommon for the infected aorta to rupture without prior aneurysm formation.
Insights
Infectious aortitis, though rare, can rupture a non-aneurysmal aorta, as seen in a Staphylococcus aureus case. Early diagnosis and high suspicion are crucial for managing this serious condition.
Area of Science:
- Cardiovascular Medicine
- Infectious Diseases
- Surgical Innovation
Background:
- Infectious aortitis is a rare condition, typically affecting immunocompromised elderly males with pre-existing cardiovascular disease and a history of specific bacterial infections.
- Staphylococcus aureus is a common pathogen implicated in such cases.
Observation:
- A 74-year-old male presented with symptoms initially misdiagnosed as a urinary tract infection and bronchitis.
- Subsequent CT imaging revealed a contained rupture of a non-aneurysmal aorta, complicated by an infected periaortic hematoma and aortic perforation.
- The patient underwent emergent surgical repair, including aortic excision, debridement, and revascularization with an ePTFE graft.
Findings:
- This case highlights that infectious aortitis can lead to aortic rupture even without a pre-existing aneurysm.
- Delayed diagnosis is a significant challenge in managing infectious aortitis.
Implications:
- A high index of suspicion is essential for the timely diagnosis of infectious aortitis.
- The findings underscore the potential for rapid aortic deterioration and rupture in infectious aortitis, necessitating prompt surgical intervention.
- This case contributes to understanding the varied presentations and potential complications of infectious aortitis.
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Aneurysm II: Clinical Manifestations and Diagnostic Studies
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