Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Small intestinal pathology.

C Okolo1, C Surawicz

  • 1Division of Gastroenterology, Harborview Medical Center, University of Washington, 325 9th Avenue, Seattle, WA 98104, USA.

Current Opinion in Gastroenterology
|October 7, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correlation of intraoperative cytological and final histological diagnoses: a retrospective 10-year study of neurosurgical cases from Ibadan, Nigeria.

Diagnostic cytopathology·2014
Same author

Hepatitis B virus transmission in pre-adolescent schoolchildren in four multi-ethnic areas of England.

Epidemiology and infection·2012
Same author

Safety and toxicity of nonoxynol-9 gel as a rectal microbicide.

Sexually transmitted diseases·1999
Same author

Bismuth binds...

The American journal of gastroenterology·1999
Same author

Trypsin activates pancreatic duct epithelial cell ion channels through proteinase-activated receptor-2.

The Journal of clinical investigation·1999
Same author

Risk of anal carcinoma in situ in relation to human papillomavirus type 16 variants.

Cancer research·1998
Same journal

Endoscopic techniques to minimize gastroesophageal reflux during peroral endoscopic myotomy.

Current opinion in gastroenterology·2026
Same journal

Postendoscopy esophageal adenocarcinoma and neoplasia: current status and future directions.

Current opinion in gastroenterology·2026
Same journal

The complement system in inflammatory bowel disease: from early observations to emerging frontiers.

Current opinion in gastroenterology·2026
Same journal

Goblet cell-associated antigen passages in health and disease.

Current opinion in gastroenterology·2026
Same journal

Inflammatory bowel diseases 2026: form, function and therapeutic considerations for the epithelial barrier.

Current opinion in gastroenterology·2026
Same journal

Dietary protein as a regulator of colitis and colorectal cancer.

Current opinion in gastroenterology·2026
See all related articles

Recent research highlights small bowel disease mechanisms, including how hypoxia affects enterocyte function and epithelial permeability. Studies also explore apoptosis, Clostridium difficile toxins, and mast cell roles in inflammation.

Area of Science:

  • Gastroenterology
  • Cellular Biology
  • Immunology

Background:

  • Small bowel diseases involve complex cellular mechanisms.
  • Enterocyte function, hypoxia, and apoptosis are key areas of study.
  • T84 cells are frequently used models for small intestinal epithelia.

Purpose of the Study:

  • To review recent advancements in understanding small bowel disease mechanisms.
  • To synthesize findings on enterocyte function, epithelial permeability, and apoptosis.
  • To highlight the roles of specific cellular components and pathogens.

Main Methods:

  • Review of recent scientific literature on small bowel disease.
  • Analysis of studies investigating enterocyte function under hypoxic conditions.
  • Examination of research on apoptosis, Clostridium difficile toxins, and mast cell activity.

Related Experiment Videos

Main Results:

  • Hypoxia alters epithelial permeability via autocrine pathways.
  • Ischemia-reperfusion induces apoptosis in small intestinal cells.
  • Clostridium difficile toxins and mast cells play significant roles in disease pathogenesis and inflammation.

Conclusions:

  • Understanding these mechanisms provides insights into cellular function and disease.
  • Further research into Clostridium difficile toxins may yield therapeutic strategies.
  • Mast cells are crucial in immune responses and postischemic inflammation.