Nonsteroidal anti-inflammatory drug gastrointestinal toxicity

B Cryer1

  • 1Medical Service, Department of Veterans Affairs Medical Center and Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75216, USA. bcryer@mednet.swmed.edu

Summary

Nonsteroidal anti-inflammatory drugs (NSAIDs) effectively reduce pain and inflammation but cause gastrointestinal toxicity. This review examines NSAID toxicity mechanisms, protective strategies, and newer NSAID developments.

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