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Enfuvirtide: patient acceptance and strategies for managing injection-site reactions
Chris Rice1, Heather Wilantewicz
1Vista Medical Partners, Beverly Hills, California, USA.
Abstract:
Enfuvirtide is a virologically and immunologically active, injectable antiretroviral fusion inhibitor developed for the treatment of HIV infection. Patients have shown high adherence rates related to self-preparation (reconstitution) and self-administration of enfuvirtide. This review discusses the efficacy and acceptability of enfuvirtide and offers advice to help health care professionals and patients address concerns about self-injection. Practical interventions that can help minimize and manage the impact of injection-site reactions are described, including the use of a needle-free device for administering the drug.
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