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ErbB-4 and TNF-alpha converting enzyme localization to membrane microdomains

Kristina W Thiel1, Graham Carpenter

  • 1Vanderbilt University School of Medicine, Department of Biochemistry, Nashville, TN 37232-0146, USA.

Biochemical and Biophysical Research Communications
|October 10, 2006
PubMed
Summary

ErbB-4 receptor processing involves sequential proteolytic cleavage. Ligand addition causes cleavable ErbB-4 to move to lipid rafts, suggesting microdomain assembly of the cleavage machinery.

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