Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The immune system and happiness.

Yoram Barak1

  • 1Psychogeriatric Department, Abarbanel Mental Health Center, Bat-Yam and the Sackler School of Medicine, Tel-Aviv University, Bat-Yam, Israel. mdybarak@netvision.net.il

Autoimmunity Reviews
|October 10, 2006
PubMed
Summary

Positive emotions, like happiness, may boost immunity by increasing secretory immunoglobulin A and decreasing stress hormones. This contrasts with negative emotions, which can impair immune response and increase illness risk.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of Metformin on Healthspan-Related Outcomes and Incidence of Diseases of Aging in People with Type 2 Diabetes Mellitus: A Systematic Review.

Rejuvenation research·2026
Same author

Allopregnanolone Concentrations After Ascending Single Dose Administration of Progesterone to Healthy Volunteers.

Human psychopharmacology·2025
Same author

Management of Relapsing Catatonia After Lorazepam Discontinuation: A Systematic Review of Published Case Reports.

Journal of the Academy of Consultation-Liaison Psychiatry·2025
Same author

Are Baby Boomers hazardous drinkers as they age? An exploratory interRAI study.

Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists·2025
Same author

Loneliness in older persons with schizophrenia.

The International journal of social psychiatry·2024
Same author

Effects of changing criteria on improving interRAI assessment for elder abuse: analysis of a national dataset from Aotearoa New Zealand.

BMJ open·2024

Area of Science:

  • Psychoneuroimmunology
  • Affective neuroscience
  • Health psychology

Background:

  • The interplay between the central nervous system and immune system is well-studied in negative emotional states like depression and schizophrenia.
  • The impact of positive emotions, particularly happiness, on physiological and immune functions remains largely unexplored.
  • Emotions significantly influence the development and progression of major diseases, including cancer, cardiovascular disease, and autoimmune disorders.

Purpose of the Study:

  • To review the relationship between affective style, psychological well-being, and immune function.
  • To investigate the physiological and immune system interactions associated with positive emotional states.
  • To explore the potential health benefits of positive emotions.

Main Methods:

  • Review of existing literature on affective style, psychological well-being, and immune markers.
  • Analysis of studies monitoring immune and endocrine systems during exposure to pleasant stimuli (e.g., odors, images).
  • Examination of physiological measures related to positive and negative affective styles.

Main Results:

  • Pleasant emotional stimuli were associated with increased secretory immunoglobulin A (sIgA) levels.
  • Exposure to pleasant stimuli led to a decrease in salivary cortisol, a stress hormone.
  • Individuals with a negative affective style may exhibit a weaker immune response and higher illness risk compared to those with a positive affective style.

Conclusions:

  • Positive emotional states show potential for beneficial effects on health through physiological and immune interactions.
  • Further research is necessary to fully understand the mechanisms linking positive emotions to immune function and health outcomes.
  • A positive affective style may be protective against illness by enhancing immune response.

Related Experiment Videos