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Published on: October 14, 2016
A case of takotsubo cardiomyopathy: transient left ventricular apical ballooning
K C H Lau1, K K H Yiu, K L Lee
1Department of Medicine, Queen Mary Hospital, Pokfulam Road, Hong Kong.
Insights
Takotsubo cardiomyopathy, or transient left ventricular apical ballooning, can mimic a heart attack. This condition may be caused by stress-induced myocardial stunning from excess catecholamines.
Area of Science:
- Cardiology
- Cardiovascular Medicine
- Internal Medicine
Background:
- Acute myocardial infarction diagnosis involves electrocardiographic and cardiac marker evaluation.
- Coronary angiography is crucial for identifying epicardial coronary artery disease.
Observation:
- A 78-year-old woman presented with chest pain and ECG changes suggestive of myocardial infarction.
- Coronary angiography showed normal epicardial arteries.
- Left ventriculography revealed apical akinesis and basal hyperkinesis.
Findings:
- The patient was diagnosed with takotsubo cardiomyopathy (transient left ventricular apical ballooning).
- This condition is potentially linked to catecholamine-mediated myocardial stunning.
Implications:
- Takotsubo cardiomyopathy presents as a distinct clinical entity mimicking acute coronary syndrome.
- Understanding its pathophysiology is vital for accurate diagnosis and management.
- This case highlights the importance of considering non-atherosclerotic causes of myocardial dysfunction.
Abstract:
A 78-year-old woman was admitted to hospital with central chest pain and the electrocardiographic and cardiac marker changes typical of acute anterior myocardial infarction. Coronary angiography revealed normal epicardial coronary arteries, and left ventriculography showed apical akinesis as well as basal hyperkinesis. This is a case of transient left ventricular apical ballooning or takotsubo cardiomyopathy, possibly attributable to catecholamine-mediated myocardial stunning.
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