Common non-synonymous polymorphisms in the BRCA1 Associated RING Domain (BARD1) gene are associated with breast

Xiang Huo1, Zhibin Hu, Xiangjun Zhai

  • 1Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.

Summary

Common genetic variations in the BRCA1 Associated RING Domain (BARD1) gene may influence breast cancer risk. Specific BARD1 polymorphisms, Pro24Ser and Arg378Ser, show a combined effect on susceptibility in Chinese women.

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