Related Experiment Video
Updated: Jul 19, 2026

Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures
Published on: November 22, 2024
Rheumatoid arthritis-associated corneal ulceration complicated by bacterial infection
Takeshi Ide1, Hiroyuki Matsuda, Kohji Nishida
1Department of Ophthalmology, Osaka University Medical School, Suita, Japan.
Abstract:
We report two cases of rheumatoid ocular disease complicated by infection of methicillin-sensitive Staphylococcus aureus (MSSA) in one case, and methicillin-resistant Staphylococcus aureus (MRSA) in the other. In both cases, punctal occlusion and immunosuppressive therapy were presumed to be major risk factors of the infections. In addition, the characteristic feature was corneal melting, which is probably accelerated by infection. To avoid infectious progression and melting, potent antibiotics followed by immunosuppressive therapy were necessary.
Related Concept Videos
Microbiome of the Eye
Rheumatic Heart Disease I: Introduction
Glaucoma: Overview