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Updated: Jul 19, 2026

An Implantable System For Chronic In Vivo Electromyography

An Implantable System For Chronic In Vivo Electromyography

Published on: April 21, 2020

Severe vocal cord dysfunction resistant to all current therapeutic interventions.

R Goldstein¹, J Bright, S M Jones

¹North West Lung Centre, Wythenshawe Hospital, Southmoor Road, Manchester, M23 9LT, UK. drgoldstein05@yahoo.co.uk

Respiratory Medicine

|October 13, 2006

Summary

Vocal cord dysfunction (VCD) causes airway obstruction and is often misdiagnosed as asthma. Despite extensive treatment, including botulinum toxin, one patient required a permanent tracheostomy due to VCD severity.

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Last Updated: Jul 19, 2026

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Published on: April 21, 2020

Area of Science:

Respiratory Medicine
Otolaryngology

Background:

Vocal cord dysfunction (VCD) involves paradoxical vocal cord adduction, leading to wheezing, stridor, cough, and dyspnea.
VCD is frequently misdiagnosed as refractory asthma, despite coexisting possibilities.
VCD significantly impacts daily activities and is challenging to manage therapeutically.

Observation:

A case study of a patient with severe VCD is presented.
The patient underwent various therapeutic interventions, including intralaryngeal botulinum toxin injections.
Despite these interventions, treatment failed to resolve the condition.

Findings:

Intralaryngeal botulinum toxin injection was ineffective in treating this severe VCD case.
The patient's VCD was refractory to all available therapeutic options.
The ultimate outcome for the patient was the necessity of a permanent tracheostomy.

Implications:

This case highlights the challenges in diagnosing and treating VCD, especially when refractory to standard and advanced therapies.
It underscores the potential for severe, life-altering outcomes in refractory VCD cases.
The case may prompt further research into alternative or more effective VCD treatment strategies.