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Related Concept Videos

Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Changes in the Appendicular Skeleton with Age01:09

Changes in the Appendicular Skeleton with Age

The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...

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Related Experiment Video

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Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

Bone health in adolescents.

Amy D DiVasta1, Catherine M Gordon

  • 1Division of Adolescent Medicine, Children's Hospital Boston, Boston, MA 02115, USA. amy.divasta@childrens.harvard.edu

Adolescent Medicine Clinics
|October 13, 2006
PubMed
Summary

Adolescence is vital for bone density. This review covers preventing bone loss in eating disorders and hormonal contraceptive effects on adolescent bone health.

Area of Science:

  • Adolescent Medicine
  • Endocrinology
  • Bone Health

Background:

  • Adolescence is critical for achieving peak bone mass.
  • Certain conditions, like eating disorders, and treatments, such as hormonal contraceptives, can negatively impact adolescent bone accrual.
  • Evaluating skeletal status in adolescents presents unique challenges due to limitations in current measurement tools.

Purpose of the Study:

  • To review medical strategies for preventing bone loss in adolescents with eating disorders.
  • To examine the skeletal effects of hormonal contraceptive agents in teenagers.
  • To highlight the importance of recognizing these risks for appropriate clinical management.

Main Methods:

  • Literature review of medical approaches for bone loss prevention in eating disorders.

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  • Review of studies on the skeletal effects of hormonal contraceptives in adolescents.
  • Synthesis of current understanding and clinical recommendations.

    • Main Results:

    • Eating disorders pose a significant risk for reduced bone density and failure to achieve peak bone mass.
    • Hormonal contraceptive agents have varying skeletal effects that require careful consideration.
    • Effective management strategies are crucial to mitigate bone loss during this critical developmental period.

    Conclusions:

    • Adolescent medicine specialists and gynecologists must be aware of factors affecting adolescent bone health.
    • Early recognition and intervention are key to preventing long-term skeletal complications.
    • Further research is needed to refine diagnostic tools and therapeutic approaches for adolescent bone health.