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Other Disorders of Digestive System

Other Disorders of Digestive System

The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...

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Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...

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Updated: Jul 19, 2026

Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice

Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice

Published on: February 3, 2016

Gastroduodenal disorders in children.

O Louis-Jacques¹, J A Perman

¹Department of Pediatrics, University of Maryland, Baltimore, Maryland 21201, USA.

Current Opinion in Gastroenterology

|October 13, 2006

Summary

Recent research reviews infantile hypertrophic stenosis mechanisms and new GI motility study tools. It also highlights Helicobacter pylori knowledge gaps and new eosinophilic gastroenteritis and food allergy cases.

Area of Science:

Pediatric gastroenterology and molecular biology.

Background:

Infantile hypertrophic stenosis mechanisms require further cellular and molecular investigation.
Understanding normal and abnormal gastrointestinal motility in infants is evolving.
Helicobacter pylori (H. pylori) research continues, yet knowledge gaps persist.

Purpose of the Study:

To review recent advancements in infantile hypertrophic stenosis.
To highlight new methods for studying infant gastrointestinal motility.
To update on Helicobacter pylori and new presentations of eosinophilic gastroenteritis and food allergy.

Main Methods:

Review of studies published within the past year.
Utilizing new modalities like electrogastrography and 13C octanoid acid breath test.
Analysis of clinical presentations and outcomes.

Related Experiment Videos

Last Updated: Jul 19, 2026

Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice

Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice

Published on: February 3, 2016

Main Results:

Progress in understanding infantile hypertrophic stenosis at cellular/molecular levels.
Characterization of gastric motility development and abnormalities in infancy.
Identification of persistent knowledge gaps regarding H. pylori transmission and outcomes.
Description of novel clinical presentations for eosinophilic gastroenteritis and food allergy.

Conclusions:

Continued research is vital for infantile hypertrophic stenosis and H. pylori.
New technologies are improving the study of infant gastrointestinal motility.
Awareness of emerging clinical presentations in pediatric gastroenterology is crucial.