Related Experiment Video
Updated: Jul 19, 2026

Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates
Published on: February 17, 2023
Gastrointestinal infections in children
1Division of Gastroenterology, University of Alabama, Birmingham, Alabama 35294, USA.
Insights
Gastrointestinal infections in children, particularly infectious diarrhea, pose significant global health risks. This review highlights recent research on causes, diagnosis, and treatment, including the role of Helicobacter pylori.
Area of Science:
- Pediatrics
- Infectious Diseases
- Gastroenterology
Background:
- Gastrointestinal infections are a leading cause of illness and death in children globally.
- Children in developing nations face higher risks due to poor sanitation and hygiene.
- Even in developed countries, diarrheal illnesses lead to frequent, costly hospitalizations.
Purpose of the Study:
- To review recent significant publications on pediatric gastrointestinal infections.
- To discuss the role of Helicobacter pylori in pediatric gastritis and peptic ulcer disease.
- To summarize current knowledge on H. pylori's natural history, symptoms, and treatment in children.
Main Methods:
- Literature review of key articles published in the past year.
- Synthesis of information on the epidemiology and etiology of infectious diarrhea in children.
- Focused discussion on Helicobacter pylori in pediatric populations.
Main Results:
- Infectious diarrhea causes substantial global child morbidity and mortality.
- Factors influencing infectious diarrhea include age, location, lifestyle, antibiotic use, and immune status.
- Helicobacter pylori is implicated in pediatric gastritis and peptic ulcer disease.
Conclusions:
- Recent research continues to refine our understanding of pediatric gastrointestinal infections.
- Helicobacter pylori is a significant pathogen in children, requiring ongoing study.
- Comprehensive approaches to diagnosis and treatment are essential for managing these infections.
Abstract:
Gastrointestinal infections in children are a major cause of morbidity and mortality worldwide. Children living in developing countries are particularly susceptible to infectious diarrhea because of poor standards of hygiene and sanitation. Although the magnitude of diarrheal illnesses in developed countries is less, costly hospital admissions are still frequent. The causal agent of infectious diarrhea is most frequently related to age, geographical location, lifestyle habits, use of antibiotics, associated medical conditions, social circumstances, and degree of immune competence. In this article we present some of the most important articles published in the field during the last year. The role of Helicobacter pylori in the pathogenesis of gastritis and peptic ulcer disease has been shown in adults and children. Information about the natural history of H. pylori, symptomatology, and diagnostic therapeutic approaches for children are being generated constantly; we discuss some of the most relevant information in this review.
Related Concept Videos
Bacterial Gastroenteritis
Giardiasis
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Microbiota of the Stomach and Small Intestine
Other Disorders of Digestive System
