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Updated: Jul 19, 2026

Synthesis of Wavelength-shifting DNA Hybridization Probes by Using Photostable Cyanine Dyes
Published on: July 6, 2016
Fluorescence of styryl dyes-DNA complexes induced by single- and two-photon excitation
V P Tokar1, M Yu Losytskyy, V B Kovalska
1Physics Department of Kyiv National Taras Shevchenko University, 2 Acad. Glushkova ave. build. 1, 03680, Kyiv, Ukraine.
Abstract:
The series of novel monomer and homodimer styryl dyes based on (p-dimethylaminostyryl) benzothiazolium residues were synthesized and studied as possible fluorescent probes for nucleic acids detection. Spectral-luminescent and spectral-photometric properties of obtained dyes in the unbound state and in DNA presence were studied. Fluorescence emission induced by two-photon excitation of dye-DNA complexes in aqueous buffer solution was registered. Two-photon absorption cross section values of the studied dyes in DNA presence were evaluated.
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