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Updated: Jul 19, 2026

Sheathless Capillary Electrophoresis–Mass Spectrometry for Metabolic Profiling of Biological Samples
Published on: October 1, 2016
Electromigration profiles of Cynomorium songaricum based on capillary electrophoresis with amperometric detection
Qingcui Chu1, Xiuhui Tian, Miao Lin
1Department of Chemistry, East China Normal University, Shanghai 200062, China.
Abstract:
A high-performance capillary electrophoresis with amperometric detection (CE-AD) method has been developed for the simultaneous determination of the pharmacologically active ingredients in Cynomorium songaricum in this work. Under the optimum conditions, phloridzin, epicatechin, catechin, naringenin, rutin, luteolin, quercetin, gallic acid, and protocatechuic acid can be well separated or nearly baseline separated (epicatechin and catechin peaks) within 31 min at the separation voltage of 14 kV in a 50 mmol L(-1) Borax running buffer (pH 9.0). Detection limits (S/N=3) ranged from 5.7 x 10(-8) to 8.5 x 10(-9) g mL(-1) for all nine analytes. This procedure was successfully used for the analysis and comparison of the content difference of C. songaricum samples collected from different places based on their electrophorograms or "electromigration profiles".
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