Obstructive jaundice caused by biliary stone formation around the stent after liver transplantation

Naoki Kawagishi1, Chikashi Matsuo, Ikuo Takeda

  • 1Division of Advanced Surgical Science and Technology, Graduate School of Medicine, Tohoku University, Sendai, Japan. kawan@mail.tains.tohoku.ac.jp

Pediatric Transplantation
|October 13, 2006
PubMed

Insights

A retained stent in a Roux-en-Y hepaticojejunostomy stump led to obstructive jaundice from a large biliary stone in a liver transplant patient. This highlights potential complications from surgical materials in biliary reconstruction.

Area of Science:

  • Hepatobiliary Surgery
  • Transplant Surgery
  • Gastroenterology

Background:

  • Biliary atresia is a severe condition requiring early intervention, often involving hepaticojejunostomy.
  • Liver transplantation (LT) is a life-saving procedure for end-stage liver disease, including biliary atresia.
  • Roux-en-Y hepaticojejunostomy is a common surgical technique used in biliary reconstruction and after LT.

Observation:

  • A 13-year-old male, post-liver transplant and hepaticojejunostomy, presented with obstructive jaundice and liver dysfunction.
  • Imaging revealed a large, rugby ball-shaped biliary stone within a dilated jejunal loop stump of the hepaticojejunostomy.
  • Surgical exploration confirmed the stone's presence and identified a previously placed hepaticojejunostomy stent within the calculus.

Findings:

  • The biliary stone was formed around a retained surgical stent within the stump of the Roux-en-Y hepaticojejunostomy.
  • Stagnated bile and anatomical variations in the jejunal loop contributed to stone formation.
  • The retained stent acted as a nidus for the biliary calculus, causing obstructive jaundice.

Implications:

  • This case underscores the importance of complete stent removal after hepaticojejunostomy to prevent long-term complications.
  • Retained surgical materials can lead to significant morbidity, including biliary obstruction and stone formation.
  • Careful surgical technique and follow-up are crucial in managing patients with complex biliary reconstructions and liver transplants.

Related Concept Videos

Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
Jaundice01:25

Jaundice

Jaundice, or icterus, is the yellow discoloration of the skin, sclerae, and mucous membranes. It happens when plasma bilirubin levels rise above 2.5-3 mg/dL, leading to bilirubin deposition in tissue.Bilirubin is a byproduct of hemoglobin degradation. In macrophages, hemoglobin breaks down into globin and heme. Globin is converted into amino acids, while heme is turned into biliverdin by heme oxygenase, which is then reduced to unconjugated bilirubin by biliverdin reductase.Unconjugated...
Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...