Related Experiment Video
Updated: Jul 19, 2026
Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
Published on: September 25, 2019
Higher prevalence of cortical lesions observed in patients with acute stroke using high-resolution diffusion-weighted
K Benameur1, J L Bykowski, M Luby
1Section on Stroke Diagnostics and Therapeutics, National Institute on Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892-1063, USA.
Abstract:
Ischemic lesion conspicuity on routine diffusion-weighted imaging (DWI, 30 seconds) was compared with an improved sequence (high-resolution DWI [DWI-HR], 256 seconds) having increased spatial resolution and signal to noise and decreased eddy current artifact in 42 patients with acute ischemic stroke. Total lesion volumes were similar; however, twice as many lesions were identified on DWI-HR, predominately in cortical gray matter. Modest improvements to imaging resulted in increased conspicuity, potentially affecting diagnosis, suspected pathogenic mechanism, and therapeutic decision.
