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Primary Culture of Rat Adrenocortical Cells and Assays of Steroidogenic Functions
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Angiotensins II and IV modulate adrenocortical cell proliferation in ovariectomized rats

A Siejka1, G Mełeń-Mucha, S A Mucha

  • 1Department of Clinical Endocrinology, Chair of Endocrinology, Medical University of Lodz, Lodz, Poland.

Journal of Physiology and Pharmacology : an Official Journal of the Polish Physiological Society
|October 13, 2006
PubMed
Summary

Angiotensin IV (AngIV) inhibits adrenocortical cell proliferation in ovariectomized rats, an effect partially reversed by losartan. Angiotensin II (AngII) showed no effect alone but, with losartan, reduced proliferation.

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