Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[Melanoma].

Toshiaki Saida¹

¹Dept. of Dermatology, Shinshu University School of Medicine.

Gan to Kagaku Ryoho. Cancer & Chemotherapy

|October 13, 2006

Summary

Recent advancements in malignant melanoma management include revised TNM staging and surgical techniques like sentinel node biopsy. While adjuvant therapies remain debated, new immunotherapies and targeted treatments show promise.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The BRAAFF-Annotated Acral Lesions Dataset (BALD): A Curated Set of Dermatoscopic Images of Acral Melanoma and Nevi from Various Sources.

The Journal of investigative dermatology·2025

Same author

Validation of a Dermatoscopy-Based Algorithm for the Diagnosis of Acral Melanoma.

Dermatology (Basel, Switzerland)·2024

Same author

Dermoscopy for Acral Melanocytic Lesions: Revision of the 3-step Algorithm and Refined Definition of the Regular and Irregular Fibrillar Pattern.

Dermatology practical & conceptual·2022

Same author

Stem cell spreading dynamics intrinsically differentiate acral melanomas from nevi.

Cell reports·2021

Same author

ALK-positive atypical Spitz tumour with conspicuous rosette-like structures.

European journal of dermatology : EJD·2021

Same author

[Melanoma and Non‒Melanoma Skin Cancers].

Gan to kagaku ryoho. Cancer & chemotherapy·2021

Area of Science:

Oncology
Dermatology
Surgical Pathology

Context:

Malignant melanoma classification and staging have undergone significant revisions.
New clinical guidelines for melanoma management have been recently proposed.
Surgical advancements aim to improve patient quality of life.

Purpose:

To summarize recent updates in malignant melanoma classification, staging, and management.
To highlight advancements in surgical procedures and adjuvant therapies.
To discuss emerging trends in immunotherapy and molecular targeting therapy for melanoma.

Summary:

The TNM classification and staging system for malignant melanoma have been fundamentally revised.
Surgical procedures such as narrow margin excision and sentinel node biopsy are improving patient outcomes.
The efficacy of high-dose interferon-alpha as adjuvant therapy is still under investigation, with ongoing research in immunotherapy and molecular targeting.

Impact:

Revised staging impacts treatment decisions and prognostic assessments for malignant melanoma patients.
Minimally invasive surgical techniques enhance recovery and quality of life.
Emerging therapies offer potential for improved treatment efficacy in advanced melanoma.

Related Experiment Videos