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Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
Published on: June 13, 2018
Skin, hair and nail fungal infections
1University of California, 1 Irving Street, AC34, San Francisco, CA 94143-0517, USA.
Abstract:
Fungal infections of the skin, hair and nails are among the most common skin diseases. The increased incidence of these infections in recent years has been attributed to the large number of immunocompromised patients, life-style changes (greater attendance at gymnasiums, public baths, etc.), the use of chemotherapeutic agents, and the greater presence of elderly people in the general population. Superficial fungal infections were also the most frequent and troublesome dermatological condition occurring among US forces during the war in Vietnam.
Insights
Superficial fungal infections, affecting skin, hair, and nails, are increasingly common. Factors like more immunocompromised individuals and lifestyle changes contribute to this rise in fungal disease.
Area of Science:
- Dermatology
- Mycology
Background:
- Fungal infections of the skin, hair, and nails are highly prevalent dermatological conditions.
- Recent years have seen an increased incidence of these superficial mycoses.
- These infections were a significant issue for US forces during the Vietnam War.
Purpose of the Study:
- To summarize the commonality and contributing factors of superficial fungal infections.
- To highlight the impact of these infections on specific populations and historical contexts.
Main Methods:
- Literature review and synthesis of epidemiological data.
- Analysis of factors contributing to the increased incidence of fungal skin diseases.
Main Results:
- Superficial fungal infections remain a leading cause of skin disease globally.
- Increased incidence is linked to a growing immunocompromised population, lifestyle changes (e.g., public bath use), chemotherapy, and an aging demographic.
- These infections posed a notable dermatological challenge in military settings, as evidenced during the Vietnam War.
Conclusions:
- Superficial fungal infections represent a significant and growing public health concern.
- Understanding the contributing factors is crucial for effective prevention and management strategies.
- The historical prevalence underscores the persistent challenge these infections pose across different populations and environments.
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