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Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...

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Updated: Jul 19, 2026

Investigating the Immunological Mechanisms Underlying Organ Transplant Rejection

Investigating the Immunological Mechanisms Underlying Organ Transplant Rejection

Published on: August 20, 2007

Infections in solid organ transplant recipients.

¹Veterans Affairs Medical Center and University of Pittsburgh, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA 15240, USA.

Current Opinion in Infectious Diseases

|October 13, 2006

Summary

Recent advances in solid organ transplant infections show human herpesvirus-6 as a cause of fever and predictor of cytomegalovirus infection. Novel therapies show promise, but antimicrobial resistance necessitates careful use.

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Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

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Last Updated: Jul 19, 2026

Investigating the Immunological Mechanisms Underlying Organ Transplant Rejection

Investigating the Immunological Mechanisms Underlying Organ Transplant Rejection

Published on: August 20, 2007

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

Area of Science:

Virology
Immunology
Transplant Medicine

Background:

Solid organ transplant recipients face significant risks from viral infections.
Emerging pathogens and evolving resistance patterns challenge current management strategies.

Purpose of the Study:

To review recent developments in understanding viral pathogenesis and therapeutic efficacy in solid organ transplantation.
To highlight novel findings regarding human herpesvirus-6, Epstein-Barr virus, hepatitis B and C viruses, and cytomegalovirus.

Main Methods:

Literature review of studies published within the past year focusing on solid organ transplant infections.
Analysis of pathogenic roles and treatment outcomes for various viral agents.

Main Results:

Human herpesvirus-6 identified as a cause of fever and predictor of cytomegalovirus infection.
Interleukin-2-primed T lymphocytes effective against Epstein-Barr virus-positive post-transplant lymphoproliferative disorder.
Hepatitis C virus treatment shows promise with interferon-alpha and ribavirin combination, while resistance to hepatitis B virus, cytomegalovirus, and azole agents is documented.

Conclusions:

New therapeutic approaches are emerging for viral infections in transplant patients.
Antimicrobial resistance necessitates judicious and selective use of prophylactic agents.