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Updated: Jul 19, 2026

Magnetic and Thermal-sensitive Poly(N-isopropylacrylamide)-based Microgels for Magnetically Triggered Controlled Release
Published on: July 4, 2017
Temperature-controlled release of diols from N-isopropylacrylamide-co-acrylamidophenylboronic acid microgels
Hui Ge1, Yanwei Ding, Chengcheng Ma
1Hefei National Laboratory for Physical Sciences at Microscale, Department of Chemical Physics, University of Science and Technology of China, Hefei, Anhui, China.
Abstract:
N-Isopropylacrylamide-co-acrylamidophenylboronic acid (NIPAM-co-PBA) microgels were prepared by free radical polymerization in water. The release of glucose and Alizarin Red S (ARS) from the microgels as a function of temperature has been investigated by using laser light scattering (LLS) and ultrasensitive differential scanning calorimetry (US-DSC). Such microgels can bind glucose and ARS via boronic acids at a lower temperature. As the temperature increases, the microgels shrink, and the diols are released. The release could be controlled by temperature. The effect of the structure of the microgels on the release is also discussed.
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