Jove
Visualize
Contact Us

Related Experiment Videos

Peripheral neuropathy associated with nodular prurigo.

A Bharati1, N J E Wilson

  • 1Dermatology Department, Broadgreen Hospital, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK. arun.bharati@rlbuht.nhs.uk

Clinical and Experimental Dermatology
|October 13, 2006
PubMed
Summary

Nodular prurigo patients often have undiagnosed peripheral neuropathy. This finding suggests thalidomide may be unsafe for many, and alternative treatments like amitriptyline or gabapentin may be beneficial.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Whole plant response of Pongamia pinnata to drought stress tolerance revealed by morpho-physiological, biochemical and transcriptome analysis.

Molecular biology reports·2022
Same author

Pyoderma gangrenosum following pacemaker insertion.

Clinical and experimental dermatology·2009
Same author

An asymptomatic eruption on the arms.

Clinical and experimental dermatology·2008
Same author

Positivity of iron studies in pruritus of unknown origin.

Journal of the European Academy of Dermatology and Venereology : JEADV·2008
Same author

A spectrum of lupus erythematosus from verrucous to systemic, coexisting with two types of porphyria.

Journal of the European Academy of Dermatology and Venereology : JEADV·2007
Same author

Multiple red-brown papules in an elderly man.

Clinical and experimental dermatology·2007
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Area of Science:

  • Neurology
  • Dermatology

Background:

  • Nodular prurigo is a pruritic skin condition.
  • Thalidomide is a treatment for severe cases.
  • Peripheral neuropathy is a known side effect of thalidomide.

Observation:

  • Nerve conduction studies were performed on eight patients with nodular prurigo considered for thalidomide treatment.
  • Five patients (62.5%) showed subclinical peripheral neuropathy.

Findings:

  • A significant subset of nodular prurigo patients exhibit subclinical peripheral neuropathy.
  • This neuropathy was present without typical symptoms or confounding medication use.

Implications:

  • Routine nerve conduction studies are crucial before prescribing thalidomide for nodular prurigo.

Related Experiment Videos

  • Alternative treatments for neuropathic pain, such as amitriptyline and gabapentin, may be suitable for patients with co-existing neuropathy.