Leg crossers' dimple: A form of localized lipoatrophy

We report eight individuals with localized lipoatrophy of the lateral lower leg that were seen by a single dermatologist in a 1-year period. All were asymptomatic and half had mild epidermal changes consistent with lichenification. Seven were an incidental finding during a general skin examination. All had a long-standing history of frequent leg crossing. The sites correlated with the area resting on the patella of the opposing knee. The depressions were larger on sides of leg-crossing preference. Only one had a significant rise in antinuclear antibodies, but this patient had no other clinical or serological abnormalities. This appears to be an extremely common yet previously unreported form of localized lipoatrophy.