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Published on: June 9, 2011
Fever of unknown origin in North Jordan
1Department of Internal Medicine, Jordan Univeristy of Science and Technology (JUST), Irbid, Jordan. fammaril21@yahoo.com
Tropical Doctor
|October 13, 2006
Summary
Infections, primarily tuberculosis, brucellosis, and typhoid fever, are the leading causes of fever of unknown origin (FUO) in Jordan. This study analyzed 52 FUO cases over seven years.
Area of Science:
- * Internal Medicine
- * Infectious Diseases
- * Epidemiology
Background:
- * Fever of unknown origin (FUO) presents a diagnostic challenge in clinical practice.
- * Identifying the etiology of FUO is crucial for effective patient management and public health.
- * Previous data on FUO causes in Jordan is limited.
Purpose of the Study:
- * To determine the most common causes of FUO among patients admitted to Basma Teaching Hospital.
- * To analyze the spectrum of diseases leading to FUO in the Jordanian population.
Main Methods:
- * Retrospective analysis of patient records.
- * Inclusion criteria: Patients admitted with a diagnosis of FUO between January 1995 and December 2001.
- * Data collected: Patient demographics, diagnostic workup, and final etiological classification.
Main Results:
- * Fifty-two patients met the FUO criteria.
- * Infections accounted for 50% of cases (26/52), with tuberculosis, brucellosis, and typhoid fever being the most frequent.
- * Malignancy (15%), connective tissue disorders (12%), and other causes (23%) comprised the remaining FUO cases.
Conclusions:
- * Infectious diseases are the predominant cause of FUO in Jordan.
- * Tuberculosis, brucellosis, and typhoid fever should be strongly considered in the differential diagnosis of FUO in this region.
- * Continued surveillance and diagnostic efforts are necessary to manage FUO effectively.
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Here are the different types of fever:
Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
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Before understanding the types and patterns of fever, it is essential to know its phases.
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A body temperature above 38°C (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.
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