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Updated: Jul 19, 2026

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
Published on: August 4, 2022
Addiction and arousal: alternative roles of hypothalamic peptides
Luis de Lecea1, Barbara E Jones, Benjamin Boutrel
1Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305, USA. llecea@stanford.edu
Abstract:
The importance of the lateral hypothalamus in the regulation of reward and motivation has long been recognized. However, the neuronal network involved in such a hypothalamic regulation of reward remains essentially unknown. Recently, hypocretin-containing neurons, a group of hypothalamic neurons known to be associated with the stability of arousal, have emerged as important structures in the control of brain reward function. This review summarizes a Mini-Symposium presented at the 2006 Annual Meeting of the Society for Neuroscience.
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