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Updated: Jul 19, 2026

In Vivo Immunofluorescence Localization for Assessment of Therapeutic and Diagnostic Antibody Biodistribution in Cancer Research
Published on: September 16, 2019
New anti-cancer therapies, new opportunities for infection
1Department of Haematology, Royal Free Hospital, London, UK.
Abstract:
Therapeutic approaches in the practice of haematology/oncology are increasing in complexity. Agents such as the purine analogues and monoclonal antibodies may introduce a new spectrum of infection as a consequence of prolonged/profound lymphoid suppression. The use of high dose therapy with stem cells support is increasing rapidly in clinical practice. Allogeneic transplantation is associated with prolonged immunosuppression and a high potential for transplant-related mortality from infection. This has led to intense interest in strategies aimed at improved prophylaxis and treatment of infective complications. This review aims to summarize recent advances in haematological practice and the effect this has had on opportunistic infections.
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