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Related Concept Videos

Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
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Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
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Updated: Jul 19, 2026

Investigating the Immunological Mechanisms Underlying Organ Transplant Rejection
05:10

Investigating the Immunological Mechanisms Underlying Organ Transplant Rejection

Published on: August 20, 2007

Infections in solid organ transplant recipients.

N Singh1

  • 1Veterans Affairs Medical Center and University of Pittsburgh, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, USA. nis5+@pitt.edu

Current Opinion in Infectious Diseases
|October 13, 2006
PubMed
Summary

Antimicrobial-resistant Gram-positive bacteria pose significant threats to transplant recipients. Emerging viruses, including human herpesviruses and a novel hepatitis virus, also present challenges in transplantation.

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Last Updated: Jul 19, 2026

Investigating the Immunological Mechanisms Underlying Organ Transplant Rejection
05:10

Investigating the Immunological Mechanisms Underlying Organ Transplant Rejection

Published on: August 20, 2007

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

Area of Science:

  • Infectious diseases
  • Microbiology
  • Transplantation immunology

Background:

  • Antimicrobial-resistant Gram-positive bacteria, such as enterococci and staphylococci, are increasingly prevalent in transplant centers.
  • These resistant pathogens pose a formidable challenge to transplant recipients, impacting patient outcomes.
  • Recent studies highlight the clinical significance of various infections in this vulnerable population.

Purpose of the Study:

  • To summarize the current challenges posed by resistant bacteria and emerging viral infections in organ transplant recipients.
  • To underscore the importance of monitoring and managing these pathogens in the context of transplantation.

Main Methods:

  • Literature review of recent publications (within the past year) focusing on infections in transplant recipients.
  • Analysis of reported trends in antimicrobial resistance and viral pathogen emergence.

Main Results:

  • Resistant Gram-positive bacteria (enterococci, staphylococci) are leading pathogens in transplant centers.
  • Human herpesvirus-6 (HHV-6) has demonstrated clinical relevance post-transplantation.
  • Human herpesvirus-8 (HHV-8) transmission via allografts can lead to Kaposi's sarcoma.
  • A novel hepatitis virus has been identified, with ongoing research into its role in transplantation.

Conclusions:

  • Transplant recipients face a dual threat from multidrug-resistant bacteria and newly identified or re-emerging viruses.
  • Vigilance and further research are crucial to address the evolving infectious disease landscape in transplantation.