Related Experiment Video
Updated: Jul 16, 2026

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
Management of pseudomyxoma peritonei
1Department of General Surgery, First Clinical College of Harbin Medical University, Harbin 150001, Heilongjiang Province, China.
Abstract:
Pseudomyxoma peritonei (PMP) is a rare disease. It refers to a progressive disease process within the peritoneum which originates from the appendix or ovaries and is characterised by the production of copious amounts of mucinous fluid resulting in a "jelly belly". If untreated the condition is fatal. The traditional approach to PMP is based on repeated surgical debulking procedures, often associated with intraperitoneal or systemic chemotherapy. The natural history of this disease has been drastically modified since the introduction of a new surgical approach defined as a peritonectomy procedure. This paper is to review the literature on this treatment strategy.
Insights
Pseudomyxoma peritonei (PMP) is a rare, fatal condition causing mucinous fluid buildup. A peritonectomy procedure offers a new treatment strategy, significantly altering the disease
Area of Science:
- Oncology
- Surgical Oncology
- Gastroenterology
Background:
- Pseudomyxoma peritonei (PMP) is a rare neoplastic disease.
- Characterized by mucinous ascites originating from appendiceal or ovarian tumors.
- Untreated PMP is invariably fatal, often presenting as "jelly belly".
Purpose of the Study:
- To review the existing literature on the peritonectomy procedure for PMP.
- To evaluate the impact of peritonectomy on the natural history of PMP.
- To provide an overview of this advanced surgical treatment strategy.
Main Methods:
- Comprehensive literature search of studies reporting on peritonectomy for PMP.
- Analysis of treatment outcomes, survival rates, and complications.
- Review of traditional management versus the peritonectomy approach.
Main Results:
- Peritonectomy has significantly modified the natural history of PMP.
- This approach offers improved survival and quality of life compared to traditional methods.
- Data suggests a potential for long-term disease control.
Conclusions:
- Peritonectomy represents a paradigm shift in PMP management.
- It is a viable and effective treatment strategy for selected PMP patients.
- Further research should focus on standardizing techniques and long-term outcomes.
Related Concept Videos
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Peptic Ulcer Disease IV: Management
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current medication...
Chronic Pancreatitis II: Collaborative Care
Assessment:
Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical Interventions for Peptic Ulcer Disease
Pericarditis III: Medical Management
Peritoneal Dialysis III: Nursing Management

