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Extradigital glomus tumors: a 20-year experience
Terry K Schiefer1, Wendy L Parker, Okechukwu A Anakwenze
1Mayo Medical School, Rochester, MN 55905, USA.
Mayo Clinic Proceedings
|October 14, 2006
Summary
Extradigital glomus tumors are uncommon but often misdiagnosed, leading to delayed treatment. Early diagnosis and surgical resection offer excellent outcomes for these painful tumors.
Area of Science:
- Oncology
- Dermatology
- Orthopedic Surgery
Background:
- Glomus tumors are rare neoplasms, with extradigital locations presenting unique diagnostic challenges.
- Delayed diagnosis of extradigital glomus tumors is common, leading to prolonged patient suffering.
Purpose of the Study:
- To review a large series of extradigital glomus tumors to understand their presentation.
- To provide guidelines for improved diagnosis and treatment of extradigital glomus tumors.
Main Methods:
- Retrospective review of extradigital glomus tumors over a 20-year period.
- Documentation of symptom incidence, duration, diagnostic imaging utility, and treatment effectiveness.
Main Results:
- Fifty-six patients with extradigital glomus tumors across various body sites were identified.
- Pain and localized tenderness were prevalent, but the classic triad was rare; average symptom duration exceeded 7 years.
- Magnetic resonance imaging (MRI) was the most effective diagnostic modality; surgical resection provided immediate and sustained pain relief.
Conclusions:
- Extradigital glomus tumors are not rare and have excellent treatment outcomes.
- Misdiagnosis and delayed diagnosis are significant issues, contributing to chronic pain and psychological distress.
- Improved diagnostic guidelines are crucial to reduce morbidity associated with delayed diagnosis.

