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[Acute myositis associated with influenza]

Seiji Noma1

  • 1Noma Children' s Clinic.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|October 14, 2006
PubMed

Insights

Benign acute myositis, a condition causing calf pain during influenza, typically affects school-aged boys and resolves within a week. Muscle damage occurs without clear viral causation, suggesting potential genetic factors.

Area of Science:

  • Virology
  • Neurology
  • Pediatrics

Context:

  • Benign acute myositis is a globally reported complication of influenza.
  • It presents with calf pain and walking difficulties during viral illness, lasting 3-8 days.
  • Mild to moderate creatine kinase elevation is characteristic, with recovery within one week.

Purpose:

  • To summarize the clinical characteristics, epidemiology, and potential pathogenesis of benign acute myositis associated with influenza.

Summary:

  • This condition predominantly affects mid-childhood (mean age 6-8 years), with a male-to-female ratio of 2.4:1.
  • Influenza B is more frequently implicated than influenza A (ratios of 6:1 and 2.4:1 reported).
  • Muscle histology shows segmental degeneration and necrosis, but a direct viral role remains unclear, hinting at genetic predisposition.

Impact:

  • Highlights the clinical presentation and epidemiological trends of influenza-associated myositis.
  • Suggests potential genetic factors influencing susceptibility in boys.
  • Informs clinical recognition and management of this benign, self-limiting condition.

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