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Updated: Jul 19, 2026

DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat (VNTR) - Fragment Length Analysis (FLA)
Published on: July 15, 2011
[Current practice of genetic diagnosis for Mycobacterium leprae]
Norihisa Ishii1, Kazue Nakanaga, Masanori Matsuoka
1Department of Bioregulation, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan. norishii@nih.go.jp
Abstract:
Laboratory tests necessary for the diagnosis of leprosy have not been well introduced in general hospitals and clinical laboratories. Therefore, several tests have been performed in Leprosy Research Center, National Institute of Infectious Diseases since July, 1997, as a part of administrative examinations (tests done by request of Ministry of Health, Labour and Welfare). These examinations include histopathology, serum antibody titers (anti-PGL-I antibody), PCR test and bioactivity of anti-bacterial agents.
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