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The multiple endocrine neoplasia syndromes

Vipul T Lakhani1, Y Nancy You, Samuel A Wells

  • 1Department of Medicine, Division of Endocrinology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.

Annual Review of Medicine
|October 14, 2006
PubMed
Summary

Genetic mutations in the menin gene cause Multiple Endocrine Neoplasia type 1 (MEN1), while REarranged during Transfection (RET) gene mutations cause MEN2 syndromes. Identifying these mutations allows for early intervention and targeted therapies.

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