[Comparison of 4 procedures in plasmapheresis: studies of modifying the hemostasis potential]

The separation of plasma using the systems "Plasmapur Monitor" (Fa. Organon), "Autopheresis-C" (Fa. Baxter) and "PCS" (Fa. Haemonetics) was compared with the conventional blood bag centrifugation. In 16 apheresis per method, several parameters with the main focus on blood coagulation were examined in addition to other criteria. Compared to conventional centrifugation of blood bags, the plasma separation machines led to an only slight activation of the coagulation system, which seems to be negligible for donors as well as recipients. Furthermore, a decrease of coagulation factors and inhibitors in the collected plasma was most pronounced using bag centrifugation. Beyond this, particularly in apheresis systems with plasma filtration the low number of remaining cells meets the aim to reach a high quality of transfused plasma.