[Selection of HLA compatible thrombocyte donors using electronic data processing with a newly developed score]

A L König1, M Holzer

  • 1Institut für Immunologie und Serologie, Universität Heidelberg.

Beitrage Zur Infusionstherapie = Contributions to Infusion Therapy
|January 1, 1990
PubMed

We developed a program for personal computers which selects platelet donors for a given patient according to the following criteria: 1. Anti-CMV-status, 2. ABO-compatibility of various degrees, and 3. HLA-incompatibility. For evaluation of HLA-incompatibility, we created a score which presently provides the following classification: 0 = identical antigen, 5 = same supertypic antigen or blank in the donor, 50 = very frequently cross-reactive antigen, 75 = frequently cross-reactive antigen, very rare antigen or antigen poorly expressed on platelets in the donor, 100 = mismatch.