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[3 new antibody detection tests. A comparative study]
Erythrocyte antibodies are of clinical importance since they may cause decreased red cell survival as the result of hemolytic transfusion reactions, hemolytic disease of the newborn or autoimmune hemolytic anemia. A variety of in vitro antibody screening tests are employed to detect their presence in donor and patient sera. Three new methods now available for pretransfusion testing--two solid phase antiglobulin tests and a gel centrifugation test--are compared in parallel with a conventional tube test.
Erythrocyte antibodies are of clinical importance since they may cause decreased red cell survival as the result of hemolytic transfusion reactions, hemolytic disease of the newborn or autoimmune hemolytic anemia. A variety of in vitro antibody screening tests are employed to detect their presence in donor and patient sera. Three new methods now available for pretransfusion testing--two solid phase antiglobulin tests and a gel centrifugation test--are compared in parallel with a conventional tube test.