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Cardiac tamponade: a life-threatening complication of Still's disease
1Division of Rheumatology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA.
Insights
Still's disease can cause pericarditis, a rare but serious complication leading to cardiac tamponade. Early recognition and aggressive treatment, including corticosteroids and procedures, are crucial for managing this life-threatening condition.
Area of Science:
- Rheumatology
- Cardiology
- Internal Medicine
Background:
- Pericarditis is a common manifestation in both adult-onset and juvenile-onset Still's disease.
- Cardiac tamponade is a rare but severe complication of pericarditis in Still's disease.
Purpose of the Study:
- To report cases of Still's disease presenting with pericardial tamponade.
- To emphasize the importance of early identification and aggressive management of pericarditis and tamponade in Still's disease.
Main Methods:
- Case report of two patients (one juvenile-onset, one adult-onset Still's disease) with pericardial tamponade.
- Literature review on pericarditis and cardiac tamponade in Still's disease.
Main Results:
- Both reported patients with Still's disease developed life-threatening pericardial tamponade.
- Literature analysis supports the association between Still's disease and pericardial complications.
Conclusions:
- Early identification of pericarditis and tamponade in Still's disease is vital.
- Aggressive intervention with corticosteroids and procedures like pericardiocentesis or pericardial window formation is recommended.
- Still's disease should be considered in the differential diagnosis for patients presenting with pericarditis and tamponade.
Abstract:
Pericarditis, a common feature of adult-onset and juvenile-onset Still's disease, is rarely complicated by cardiac tamponade. We report one patient with juvenile-onset and another with adult-onset Still's disease presenting with pericardial tamponade. On the basis of our experience and analysis of literature, we suggest early identification of pericarditis and the life-threatening complication of tamponade, with institution of aggressive intervention with corticosteroids and, if necessary, pericardiocentesis and pericardial window formation. These cases remind physicians about the need to include Still's disease in the differential diagnosis of pericarditis and tamponade and to not neglect the potential of severe systemic inflammation to lead to fatal complications in this group of patients.
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