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[Quality of thrombocyte preparations from buffy coat or platelet-rich plasma]
1Institut für Klinische Immunologie und Transfusionsmedizin Justus-Liebig-Universität, Giessen.
One hundred platelet concentrates, fifty prepared from buffy coat and fifty prepared from platelet-rich plasma were examined. In platelet concentrates from buffy coat a lower leukocyte contamination (1.4 +/- 1.2 x 10(7) vs 13.2 +/- 15 x 10(7], a significant higher ATP content (6.3 +/- 1.7 mmol/10(14) platelets vs 3.9 +/- 1.9 mmol/10(14) platelets) and a better response in ADP- or collagen-induced aggregation could be determined during storage of five days. Our results indicate that preparation of platelet concentrates from buffy coat is preferable to their preparation from platelet-rich plasma.
One hundred platelet concentrates, fifty prepared from buffy coat and fifty prepared from platelet-rich plasma were examined. In platelet concentrates from buffy coat a lower leukocyte contamination (1.4 +/- 1.2 x 10(7) vs 13.2 +/- 15 x 10(7], a significant higher ATP content (6.3 +/- 1.7 mmol/10(14) platelets vs 3.9 +/- 1.9 mmol/10(14) platelets) and a better response in ADP- or collagen-induced aggregation could be determined during storage of five days. Our results indicate that preparation of platelet concentrates from buffy coat is preferable to their preparation from platelet-rich plasma.