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[Microscopic colitis. A 20 cases series].

Monia Fekih1, Fethia Ben Hriz, Amel Sassi

  • 1Service de Gastro-entérologie A. Hôpital la Rabtu, Tunis.

La Tunisie Medicale
|October 17, 2006
PubMed
Summary
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Microscopic colitis, characterized by chronic inflammation with normal-appearing colonic lining, often presents with chronic diarrhea. Sulphasalazine showed a 41.2% remission rate in patients with microscopic colitis.

Area of Science:

  • Gastroenterology
  • Pathology

Context:

  • Microscopic colitis involves chronic inflammation of the colon, not visible during standard endoscopic examination.
  • Diagnosis relies on histological analysis of colonic biopsies.

Purpose:

  • To report findings from 20 cases of microscopic colitis.
  • To describe the clinical presentation, diagnostic methods, and treatment outcomes.

Summary:

  • Chronic diarrhea was the primary symptom in 95% of patients.
  • Collagenous colitis accounted for 65% of cases, and lymphocytic colitis for 35%.
  • Sulphasalazine treatment resulted in clinical remission in 41.2% of patients.

Impact:

  • Highlights the diagnostic challenge of microscopic colitis due to normal endoscopic findings.

Related Experiment Videos

  • Provides evidence for sulphasalazine as an effective treatment option for microscopic colitis.
  • Contributes to understanding the prevalence of different microscopic colitis subtypes.