[Prune belly syndrome: early prenatal diagnosis and management]

Area of Science:

• Medical Genetics
• Prenatal Diagnosis
• Pediatric Surgery

Background:

• Prune Belly syndrome is a rare congenital disorder.
• It is characterized by abdominal wall muscle deficiency, urinary tract abnormalities (like megacystis), and undescended testes (bilateral cryptorchidism).

Observation:

• The study presents two cases of Prune Belly syndrome.
• These cases were diagnosed at 11 and 14 weeks of gestation.
• Diagnosis is typically easier after 15 weeks but can be challenging earlier.

Findings:

• Early diagnosis of Prune Belly syndrome is feasible.
• The cases demonstrate successful prenatal identification at 11 and 14 weeks.
• Literature review supports early diagnostic possibilities.

Implications:

• Earlier diagnosis allows for timely genetic counseling and management planning.
• Improved understanding of Prune Belly syndrome diagnosis aids in better prenatal care.
• This research can inform obstetricians and geneticists about early detection markers.